Comparison of clinical application of iRoot SP, GuttaFlow 2 and AH Plus root canal sealer / 口腔疾病防治

Objective@# The short-term clinical effects of two kinds of normal temperature flow root sealers (the calcium silicate-based sealer iRoot SP and the siloxane-based sealer GuttaFlow2) combined with single point filling technology and a frequently-used sealing agent (AH Plus) combined with continuous wave hot tooth filling technology were evaluated. @*Methods @#A total of 279 teeth (656 root canals) were randomly divided into three groups: the iRoot SP group, GuttaFlow2 group and AH plus group. We recorded the filling time of each root canal, collected a digital dental film to evaluate the filling effect of each root canal, and conducted a follow-up visit one week and one month after the operation to record the incidence of pain. We used SPSS 18.0 to analyze the above data. @*Results @# There was no significant difference in the root canal filling effect among the three groups (P > 0.05). There was no significant difference in the filling time between the iRoot SP group and the GuttaFlow2 group (P > 0.05), but the filling time was significantly shorter in the AH Plus group (P < 0.05). There was no significant difference in the postoperative pain between the iRoot SP group and the GuttaFlow2 group (P > 0.05), and the incidence of pain in the iRoot SP group and the GuttaFlow2 group was lower than that in the AH Plus group (P < 0.05).@*Conclusions @# GuttaFlow2 and iRoot SP combined with single point filling technology can save filling time and obtain good clinical effects compared with frequently-used hot tooth filling technology and the incidence of postoperative pain was low.

The Effect of AH Plus and GuttaFlow Bioseal Sealers on the Fracture Resistance of Endodontically Treated Roots Instrumented with Reciprocal Rotary Systems

Objective: The objective of this study was to assess and compare the fracture resistance of roots treated endodontically using WaveOne gold, Reciproc blue, AH plus sealer and GuttaFlow Bioseal sealer. Materials and methods: Total 48 human mandibular premolars with single root were decoronated to a length of 13 mm. The roots were arbitrarily divided into 3 main groups (n=16 each group). Group I control group (roots were instrumented but not obturated), Group II obturated with gutta-percha and GuttaFlow Bioseal sealer and Group III obturated with gutta-percha and AH plus sealer. Each main group was additionally divided into 2 subgroups (n=8 each subgroup) conforming to the system used in root canal preparations, Subgroup A: Reciproc blue system and Subgroup B: WaveOne gold system. All root samples were kept for 1 week at 100% humidity to permit the sealers to set completely. Each sample was then exposed to fracture test utilizing a universal test machine, the data were analyzed statistically with one-way ANOVA test, two-way ANOVA test and Dunnett test (2-sided) at a significant level of 0.05. Results: The results revealed that the highest mean value of fracture resistance was noted in Group IIIB (611.125) followed by Group IIIA (543.250), Group IIB (519.875), Group IIA (511.875), Group IB (270.125) and Group IA (267.875) respectively with statistically highly significant differences among the different groups when compared to the control group. Conclusion: From the results of this study, it seems that the use of AH plus and GuttaFlow Bioseal sealers improved the fracture strength of instrumented roots whereas preparation of the root canals with WaveOne gold and Reciproc blue systems without obturation weakened the tooth structures.

Apical sealability in extracted teeth by the root canal filling agents GuttaFlow and AH Plus: a systematic review / 口腔疾病防治

Objective@#To compare the apical sealing effects of two root canal fillers, GuttaFlow and AH Plus, for clinical reference.@* Methods@#The Cochrane system evaluation method was used to search the Cochrane Library, Embase, CBM, PubMed, CNKI, Weipu, and Wanfang databases. Additionally, relevant journals and conference papers were manually retrieved, and relevant randomized controlled trials were collected. Two reviewers independently evaluated the quality of each study and extracted the data. A meta-analysis was performed using the RevMan5.3 software for homogenous studies, and a descriptive analysis was performed for studies with poor homogeneity.@*Results@#In total, 10 randomized controlled trials containing 398 isolated teeth were included. The meta-analysis results showed that the difference in apical microleakage was statistically significant at 1 week and 3 months [1 week: MD=-0.13, 95% CI (-0.22,-0.04), P=0.007; 3 months: MD=-1.27, 95% CI (-1.94,-0.60), P=0.000 2] but not at 6 months [MD=-0.10, 95% CI (-0.26, 0.06), P=0.23].@* Conclusion@#Based on existing research results, GuttaFlow may achieve better results than AH Plus in the short term (≤ 1 week). Because it is subject to limitations of time, quality, and research methods, this conclusion requires more long-term, high-quality, large-sample, multimeasurement randomized controlled trials for further validation.

The effect of different final intracanal irrigants on the bond strength of silicone-based sealer to root canal walls / 天津医药

Objective To evaluate the bond strength of GuttaFlow sealers to root canal walls after final rinse with two novel fi nal irrigation regimens, QMiX and 17%EDTA+0.2%Cetrimide (CTR). Methods Thirty single-canal teeth were prepared chemomechanically using 5.25% sodium hypochlorite (NaOCl) as root canal irrigants. The teeth were then randomly distributed into three groups(n=10)according to the final irrigation protocol:QMiX group,17% EDTA followed by CTR group and control group(normal saline,NS).After the filling with GuttaFlow using a lentulo spiral,the roots were transversally sectioned to obtain 2 mm thick dentinal slices.Then a push-out bond strength test was carried out,and failure mode was determined at×24 magnification.Results The push-out bond strength was significantly higher in QMiX group than that of EDTA+CTR group and NS group(P<0.05),and no significant difference was observed between EDTA+CTR and NS groups(P>0.05).The failure patterns were mainly mixed.Conclusion The QMiX,as the final irrigant,can improve the bond strength of silicone-based sealer GuttaFlow.

Effects of different root canal filling stop on quality of root canal filling in root canals obturated with GuttaFlow / 口腔疾病防治

Objective @# To investigate the effects of different root canal filling stop on quality of root canal filling and apical sealing in root canals obturated with GuttaFlow. @* Methods@#60 teeth were randomly divided into three groups, using different root canal filling stops to shape the root canals with MTwo (25/06) file. All root canals were obturated with Gutta Flow, and the overfilling of the root canals were recorded and evaluated by X-ray. And the apical microleakage of teeth was evaluated by transparent teeth technique.@*Results@#The roots were prepared with MTwo (25/06) as master apical file, the overfilling rate of the root canals in root canal filling stop was higher as the distance from the apex was shorter, but there was no significant difference. The under-filling rate of the root canals in root canal filling stop was higher as the distance from the apex was longer. And the under-filled root canals in root canal filling stop 0.5 mm from the apex showed a statistically significant difference with 2 mm. The mean dyeing penetration length in 0.5 mm and 1 mm group was significantly shorter than 2 mm group. @*Conclusion @#A suitable root canal filling stop could improve the quality of root canal filling in root canals obturated with GuttaFlow.

Biological Tissue Response to a New Formulation of a Silicone Based Endodontic Sealer

Abstract Satisfactory biological behavior is a necessary requirement for clinical application of endodontic materials. In this study, the connective tissue responses to silicone (GuttaFlow 2), epoxy resin (AH Plus) and zinc oxide and eugenol (Endofill) based sealers were compared. Twelve Wistar rats had polyethylene tubes (four per animal) containing one of the tested sealers and empty tubes (negative control) implanted in their subcutaneous tissue. The tubes were randomly placed 2 cm from the spine and at least 2 cm apart from one another. Tissue samples with implants were processed for histological analysis after 7 or 60 days (n=6 animals per period). Inflammatory cells, fibrous condensation and abscess were scored according to their intensity. Friedman, followed by Dunn's post hoc, was used to compare sealers. Differences between the two experimental periods were verified using Mann-Witney U test (p<0.05). At 7 days, most of the histological parameters showed no significant differences amongst groups. Endofill group scored higher than the others for giant cells (o<0.05) and promoted a greater number of samples presenting abscess formation. GuttaFlow 2 tended to show a less intense inflammatory infiltrate compared to the other materials. At 60 days, there were no significant differences between groups in most of the histological parameters evaluated. However, it was observed that Endofill scored higher for macrophages (p<0.05) compared to the control group, and GuttaFlow 2 tended to present lower scores than the others for neutrophils and abscess. GuttaFlow 2 showed proper biological behavior and should be considered adequate for clinical practice.

Resumo Um dos requisistos para a aplicação clínica de materiais endodônticos é apresentar comportamento biológico satisfatório. Neste estudo, as respostas do tecido conjuntivo a cimentos endodônticos à base de silicone (GuttaFlow 2), resina epóxica (AH Plus) e óxido de zinco e eugenol (Endofill) foram comparadas. Doze ratos Wistar tiveram tubos de polietileno (4 em cada animal) contendo um dos materiais e tubos vazios (controle negativo) implantados no tecido conjuntivo subcutâneo. Os tubos foram randomicamente posicionados pelo menos 2 cm distantes entre si e da espinha dorsal do animal. Amostras de tecido contendo os implantes foram processadas para análise histológica após 7 e 60 dias (n=6 animais por período). Células inflamatórias, condensação fibrosa e formação de abscesso foram classificadas em escores de acordo com sua intensidade. O teste Friedman, seguido por post hoc de Dunn, foi empregado para comparar os cimentos. O teste de Mann-Witney U foi empregado para verificar diferenças entre os períodos experimentais em cada grupo (p<0,05). Após 7 dias, a maior parte dos parâmetros histológicos não mostrou diferenças estatísticas entre os grupos. O cimento Endofill promoveu escores mais altos que os outros materiais para a variável células gigantes (p<0,05), além de apresentar um maior número de amostras com formação de abscesso. O GuttaFlow 2 tendeu a apresentar infiltrado inflamatório menos intenso comparado aos outros materiais. Após 60 dias, não houve diferenças estatisticamente significantes entre os grupos na maioria dos parâmetros avaliados. Entretanto, observou-se que o EndoFill apresentou escores mais altos para os macrófagos em comparação ao controle (p<0,05) e que o GuttaFlow 2 apresentou tendência a escores mais baixos que os demais materiais para as variáveis neutrófilos e abscesso. O GuttaFlow 2 apresentou propriedades biológicas apropriadas e pode ser considerado adequado para a prática clínica.

The effects of different final irrigation regimens on the bond strength of sealers to root canal walls / 实用口腔医学杂志

Objective:To evaluate the bond strength of root canal sealer AH Plus and GuttaFlow to root canal walls after final rinse with 4 different final irrigation regimens.Methods:60 teeth with single-canal were prepared chemomechanically using 5.25% sodi-um hypochlorite (NaOCl)as root canal irrigant.The teeth were then randomly distributed into 3 groups(n =20)according to the final irrigation protocol:1 7% EDTA followed by 2% chlorhexidine(CHX)(group 1 ),5.25% NaOCl followed by 1 7% EDTA(group 2), 0.9% normal saline(NS)(group 3).The root canals were then filled with sealers using a lentulo spiral and each group was distribu-ted into 2 subgroups according to the sealers(n =1 0):a.AH Plus;b.GuttaFlow.The roots were transversally sectioned to obtain 2mm thick dentinal slices.Then a push-out bond strength test was carried out and failure mode was observed by stereomicroscope. Results:The bond strength of AH Plus was significantly higher than that of GuttaFlow(P 0.05).When the root canals were filled with GuttaFlow,the push-out strength of group 1 ,2 and 3 was (1 .40 ±0.59)MPa, (1 .26 ±0.62)MPa and (1 .05 ±0.27)MPa respectively(P >0.05).The failure modes of AH Plus and GuttaFlow were both mainly mixed,but the proportion of adhesive failure in the canals filled with GuttaFlow were obviously higher than AH Plus.Conclusion:The bond strength to root canal wall of GuttaFlow is significantly lower than that of AH Plus.1 7% EDTA followed by 2% CHX as fi-nal irrigant can reduce the bond strength of AH Plus but has no marked effect on GuttaFlow.

Sealing ability of different versions of GuttaFlow2 in comparison to GuttaFlow and AH Plus

Introduction and objective: GuttaFlow2 is a further development of the silicone sealer GuttaFlow, exhibiting a stiffer consistency. This is intended to overcome possible problems regarding retention of the apical part of the root canal filling when preparing for a fiber post. GuttaFlow2 is delivered within a capsule, like GuttaFlow, or within an automix syringe. This study compared apical dye leakage of GuttaFlow2 in comparison to GuttaFlow and AH Plus. The null hypothesis tested was that different sealers exhibited similar microleakage. Material and methods: Seventy extracted human lower premolars with fully mature apices were root canal prepared to 45/.04 and divided into seven groups: group 1: AH Plus sealer, group 2: "normal" setting GuttaFlow, group 3: "fast" setting GuttaFlow, group 4: GuttaFlow2 within a capsule, group 5: GuttaFlow2 within an automix syringe, group 6: positive control, group 7: negative control (n = 10 each). Root canals were filled with sealer (except group 7) and a master gutta-percha cone size 40/.04 using the non-compaction technique. A dye penetration test was carried out by centrifugation for 3 min at 30 G within 5 % methylene blue dye. Linear dye penetration was recorded. Statistical evaluation was carried out with IBM SPSS 19.0 (α = 0.05). Results: The positive control was significantly different from all other groups (ANOVA, p < 0.001; Student-Newman-Keuls post-hoc test p < 0.05). When the control groups were disregarded, no significant differences were apparent. Groups 1 to 5 showed low leakage values when compared with results of earlier studies using a similar methodology. Conclusion: All sealers tested exhibited low dye leakage values.

An ex vivo evaluation of the sealing ability of polydimethylsiloxane-based root canal sealers.

Aim: The aim was to study the sealing efficacy of polydimethylsiloxane‑based root canal sealers. Materials and Methods: Polydimethylsiloxane‑based root canal sealers were reviewed and subjected to an ex vivo study. A total of 60 extracted maxillary incisors were included in this study, which was conducted under two groups, Groups A and B, of 30 teeth each. In Group A, GuttaFlow and in Group B, RoekoSeal as sealers were used for obturation with Gutta‑percha cones after preparing canal with a step back technique. The criterion for evaluating sealing efficacy of the sealers was light absorption by spectrophotometer. The collected data were analyzed statistically using one‑way ANOVA test. Results: The findings of the study revealed that the mean leakage in Group B (0.1027) was significantly less than Group A (0.1649) (P < 0.001). RoekoSeal showed superior sealing ability. Conclusion: RoekoSeal had the better sealing ability than GuttaFlow and may be recommended for clinical use.

A SEM evaluation of dentinal adaptation of root canal obturation with GuttaFlow and conventional obturating material.

Objective: The aim of this in-vitro study was to compare dentinal adaptation of conventional obturating material and GuttaFlow in young permanent teeth of child patients. Materials and Methods: Ten young permanent anterior teeth with closed foramen were selected for the study. Root canal preparations were carried out using a step back technique. The canal was alternately irrigated with 5.25% sodium hypochlorite solution and 17% EDTA and normal saline. After root canal preparation specimens were randomly divided into two groups (n=5). GROUP "A": Obturated with zinc-oxide eugenol sealer and gutta-percha cone using cold lateral obturation technique. GROUP "B": Obturated with GuttaFlow as per the manufacturer's instruction. The teeth were split into two halves. Five randomly chosen longitudinal split teeth samples each from Group "A" and Group "B" was observed under scanning electron microscope to access the interface between obturating material and dentin at the level of 2 mm from the apex. Results: On statistical analysis the dentinal adaptation (μm) of Group A was observed with a mean of 0.52 and standard deviation 0.15, while the value of mean and standard deviation were noted 0.12 and 0.02 for Group B. The "t" value on comparison of Group A and Group B is 5.79 with "P " value of <0.001, which is highly significant. Conclusion: From result of the study it can be concluded Group B samples showed significantly superior seal when compared with Group A. Complete seal was not observed in any of Group A samples.

Evaluación in vitro de la filtración coronaria a través de dos técnicas de obturación de gutapercha plastificada: híbrida de tagger y guttaflow / In vitro evaluation of coronary filtration through two sealing techniques plasticized gutta percha: Hybrid tagger and GuttaFlow

El objetivo de este trabajo fue evaluar la filtración vía coronaria de dos técnicas de obturación diferentes: la técnica Híbrida de Tagger y el Sistema Guttaflow. Cincuenta primeros premolares inferiores humanos fueron preparados con la técnica crown-dowm y divididos aleatoriamente en dos grupos de 20 dientes. Otros 5 dientes fueron utilizados como grupo control negativo y otros 5 dientes como grupo control positivo. El grupo 1 fue obturado con la técnica Hibrida de Tagger con Sealer 26 como cemento obturador y el grupo 2 fue obturado con el sistema Guttaflow. Los dientes fueron restaurados de forma provisional con Coltosol y colocados en una estufa a 37° C con una humedad de 95%. Después de permanecer 30 días en la estufa, fue retirada la restauración provisional y los dientes fueron dejados en la estufa por 30 días más. Fue realizada la impermeabilización con cianoacrilato de etilo. Los dientes fueron inmersos en rodamina b al 2% durante 72 horas. Cada diente fue cortado de mesial a distal para observar el grado de filtración. Los dientes fueron escaneados y medidos mediante el software Image Tools Image Tools v.3.00. Las dos técnicas de obturación permitieron una filtración del colorante vía coronaria; pero entre los dos grupos se observó una diferencia estadística importante. En el grupo 1 (Hibrida de Tagger) se observó una filtración promedio de 0,96 mm y en el grupo 2 (Guttaflow) se observó una infiltración promedio de 2,36 mm. Los resultados mostraron que la técnica Híbrida de Tagger ofreció un mejor sellado de los conductos en comparación al sistema GuttaFlow

The purpose of this research was to evaluate the coronary's infiltration of two different filling techniques, the Tagger´s Hybrid technique and the Guttaflow System. Fifty inferior premolar human teeth were prepared using the crown-down technique, and then divided into two groups of twenty each. Five extra teeth were used as a positive control group, and other five as a negative control group. The first group was filled with the Tagger´s Hybrid technique using Sealer 26 as a root filler compound. On the other hand, Guttaflow System was used on the second group. All of the teeth were temporary restaured with Coltosol and placed in a stove at 37º C and 95 % humidity. After 30 days in the stove, the temporary filling was removed and remained for another 30 days. The impermeabilization was made with ethil of cyanoacrylate . All the teeth were immersed in 2% Rodamine b for 72 hours. Each tooth was cut from mesial to distal side to observe the infiltration amount. The teeth were scaned and measure by Image Tools v.3.00 software. The two filling techniques allowed colorant infiltration throw the crown; but was observed an important statistic difference. The first group (Tagger´s Hybrid technique) showed an average infiltration of 0.96mm and the second group (Guttaflow) 2.36mm. The results of this research showed that the Tagger´s Hybrid technique presented less coronary's infiltration than the Guttaflow

Evaluation of single root canals filled using the lateral compaction, tagger's hybrid, microseal and guttaflow techniques

The aim of this study was to determine the percentage of voids, gutta-percha and root canal sealer using 4 different filling techniques. Fifty-two extracted maxillary lateral incisors were prepared using the crown-down pressureless technique. The teeth were randomly divided in 4 groups (n=13): Lateral compaction (LC), Tagger's hybrid (TH), MicroSeal (MS) and GuttaFlow (GF) techniques. Horizontal cross-sections were made at the 2, 10 and 15 mm levels from the apex. Digital images of the root canal areas were acquired using a stereomicroscope and examined using the Image Tool 3.0 software. Statistical analysis was performed using the Kruskal-Wallis test (α=0.05). In general, a significant decrease in the gutta-percha filled area and increase of sealer area were observed at the apical level for all the evaluated techniques (p<0.05). With regard to the presence of voids, no significant difference was found. MS and TH techniques showed a larger gutta-percha filled area than LC and GF techniques at the coronal and middle third level (p<0.05). From the results of the present study, it may be concluded that the gutta-percha filled area of fillings decrease at the apical level, regardless of the filling technique used.

O objetivo do estudo foi determinar a porcentagem de espaços vazios, guta-percha e cimento após a obturação por 4 diferentes técnicas. Cinquenta e dois incisivos laterais superiores humanos extraídos foram instrumentados pela técnica coroa-ápice sem pressão. Os dentes foram randomicamente divididos em 4 grupos (n=13): Condensação lateral (LC), Técnica híbrida de Tagger (TH), MicroSeal (MS) e GuttaFlow (GF). Foram feitas secções horizontais a 2, 10 e 15 mm do ápice. Imagens digitais foram obtidas dos canais por meio de estereomicroscópio e analisadas no programa Image Tool 3.0. A análise estatística foi feita utilizando o teste de Kruskal-Wallis (α=0,05). Em geral foi observado um significante decréscimo na área de guta-percha e um aumento na área de cimento para todas as técnicas analisadas (p<0,05). Com relação à presença de espaços vazios, não houve diferença estatística entre as técnicas (p>0,05). As técnicas MS e TH apresentaram área de guta-percha maior que as técnicas LC e GF nos terços médio e cervical (p<0,05). Após análise dos resultados foi possível concluir que a área de guta-percha nas obturações diminui em sentido apical, independente da técnica utilizada.